KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCG2
All Species:
36.06
Human Site:
Y576
Identified Species:
61.03
UniProt:
Q9UNQ0
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UNQ0
NP_004818.2
655
72314
Y576
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
Q
H
Chimpanzee
Pan troglodytes
XP_526633
860
94544
Y781
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
Q
H
Rhesus Macaque
Macaca mulatta
Q5MB13
654
72441
Y575
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
Q
H
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q7TMS5
657
72959
Y576
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
Q
Y
Rat
Rattus norvegicus
Q80W57
657
72942
Y576
Q
Y
F
S
I
P
R
Y
G
F
T
A
L
Q
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510302
654
72378
Y574
K
Y
F
S
I
P
R
Y
G
F
A
A
L
Q
Y
Chicken
Gallus gallus
XP_421638
651
72109
Y579
K
Y
F
S
I
P
R
Y
G
L
T
A
L
Q
V
Frog
Xenopus laevis
NP_001091141
661
73548
Y576
K
Y
F
S
I
P
R
Y
G
L
T
A
L
Q
V
Zebra Danio
Brachydanio rerio
NP_001036240
643
71395
Y569
K
Y
F
S
I
P
R
Y
G
L
S
A
L
Q
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P10090
687
75654
Y612
S
Y
L
S
W
F
R
Y
A
N
E
G
L
L
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q11180
598
66888
D529
A
L
A
I
N
E
W
D
S
I
K
V
I
P
E
Sea Urchin
Strong. purpuratus
XP_789781
628
69714
N559
S
I
I
R
Y
S
V
N
A
L
S
I
N
E
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q93YS4
751
82913
G675
V
M
T
F
M
L
A
G
G
F
F
V
K
K
V
Baker's Yeast
Sacchar. cerevisiae
P25371
1049
117213
Y976
L
K
N
F
S
V
F
Y
Y
A
Y
E
S
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.4
96.6
N.A.
N.A.
81.8
81.4
N.A.
75.8
62.4
68.2
60.9
N.A.
31.5
N.A.
29.6
45
Protein Similarity:
100
75.9
97.7
N.A.
N.A.
89.6
89.1
N.A.
88.2
78.3
82.1
77.8
N.A.
51.6
N.A.
48.4
63.8
P-Site Identity:
100
100
100
N.A.
N.A.
93.3
100
N.A.
80
80
80
73.3
N.A.
33.3
N.A.
0
0
P-Site Similarity:
100
100
100
N.A.
N.A.
100
100
N.A.
93.3
86.6
86.6
86.6
N.A.
33.3
N.A.
6.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.7
23.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
47.5
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
0
15
8
8
65
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
8
0
0
0
0
8
8
0
8
8
% E
% Phe:
0
0
65
15
0
8
8
0
0
50
8
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
72
0
0
8
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
29
% H
% Ile:
0
8
8
8
65
0
0
0
0
8
0
8
8
0
15
% I
% Lys:
29
8
0
0
0
0
0
0
0
0
8
0
8
8
0
% K
% Leu:
8
8
8
0
0
8
0
0
0
29
0
0
72
15
8
% L
% Met:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
8
0
0
8
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
65
0
0
0
0
0
0
0
8
0
% P
% Gln:
36
0
0
0
0
0
0
0
0
0
0
0
0
65
0
% Q
% Arg:
0
0
0
8
0
0
72
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
0
72
8
8
0
0
8
0
15
0
8
0
0
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
50
0
0
0
0
% T
% Val:
8
0
0
0
0
8
8
0
0
0
0
15
0
0
22
% V
% Trp:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
72
0
0
8
0
0
79
8
0
8
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _